ESPEYB15 1 Pituitary and Neuroendocrinology (1) (1 abstracts)
1. Pituitary and Neuroendocrinology
Nicolas de Roux a , Evelien F Gevers b & Carles Gaston-Massuet c
aBiochemistry Laboratory, INSERM U1141, Université Paris Diderot, Sorbonne Paris Cité, Paris, France
bDepartment of Paediatric Endocrinology, The Royal London Hospital, Barts Health Trust, London, UK
cDepartment of Endocrinology, William Harvey Research Institute, Queen Mary University London, London, UK
This year has been very rich in highly interesting papers in Neuroendocrinology. Some papers reported in this selection described new mechanisms, but also new mouse models to understand or to investigate pediatric endocrinopathies. In these 12 papers, one of them stands out as highly remarkable by the originality of the hypothesis, the quality of the work but also for the perspectives in medicine. This paper by Zhang et al. demonstrates the importance of hypothalamic stem/progenitor cells in the control of ageing and the involvement of exosomal microRNA secreted by these cells in this process. Although this study has been performed in adult mice, we may speculate similar mechanisms may be involved in humans. In this selection, we also report papers on new mouse models which pave the way for the development of novel treatments in rare neuroendocrine diseases.
Volume 15
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ESPE Yearbook of Paediatric Endocrinology
ISSN 1662-4009 (Online)
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