ESPEYB15 1 Pituitary and Neuroendocrinology Reviews (3 abstracts)
Department of Pediatric Endocrinology, University Children’s Hospital, Tubingen, Germany.
Department of Pediatrics, Leiden University Medical Center, Leiden, Netherlands
To read the full abstract: Nat Rev Endocrinol 2018;14:285-300
This is an interesting review of the history of research in the field of GH-IGF1 and the clinical use of GH. It comprises a timeline starting in 1884 with the description of dwarfism (General Tom Thumb) and gigantism, and ending in 2015-16 describing the discovery of paternally inherited IGF2 mutations and PAPPA-2 mutations as causes for short stature. This is a pleasure to read, and you are sure to learn something new.