ESPE Yearbook of Paediatric Endocrinology

Preface: In the puberty field, this year brought new evidence regarding the link between obesity and the onset of puberty. Several high impact basic studies identified new factors involved in the hypothalamic crosstalk between the control of puberty and energy balance.

This chapter also summarizes the discoveries regarding the genetic architecture of hypogonadotropic hypogonadism and central precocious puberty and presents some studies looking at the effects of environmental factors such as physical activity or endocrine disrupting chemicals on pubertal development. New perspectives opened up regarding the treatment of boys with constitutional delay of growth and puberty with aromatase inhibitors.