Pediatric Endocrinology and Diabetology, University Childrens Hospital Basel, University Basel, Basel Switzerland and Department of Clinical Research, University Hospital Basel, Basel, Switzerland
Preface: This years THYROID chapter aims at summarizing important new knowledge on all aspects of the thyroid axis from fundamental and clinical research relevant for scientists and clinicians, ranging from studies on the function of primary cilia within the thyroid follicle over new genetic defects along the thyroid axis to new immunmodulatory therapeutic approaches for Graves disease. These new insights provide better molecular understanding of thyroid hormone regulation and action in health and disease eventually opening new avenues of research and will hopefully add to improved clinical diagnosis and more stratified management of children affected by thyroid diseases.