ESPEYB17 7. Puberty Sara Moline, Delphine Franssen, Anne-Simone Parent (1 abstracts)
aDepartment of Pediatrics, University Hospital Liège, Belgium; bNeuroendocrinology Unit, GIGA-Neurosciences, University of Lieège, Belgium
Preface: In the puberty field this year, several high impact basic studies highlighted the role of neurotrophic factors and microRNA in GnRH neuron migration and activation around puberty. Fascinating discoveries were made regarding the transcriptome of developing GnRH neurons and testicular cells.
This chapter also summarizes new data regarding the genetic architecture of the control of puberty using GWAS studies in boys as well as much awaited data regarding estrogen reference values in children and sertoli function in boys with constitutional delay of growth and puberty treated with aromatase inhibitors.