ESPEYB21 7. Puberty Julie Fudvoye, Caroline Gernay, Anne-Simone Parent (1 abstracts)
7. Puberty
Julie Fudvoye 1,2 , Caroline Gernay 1 & Anne-Simone Parent 1,2
1Department of Pediatrics, University Hospital Liège, Belgium; 2.Neuroendocrinology Unit, GIGA-Neurosciences, University of Liège, Belgium
Introduction
This year clinical studies explored further some persistent questions regarding the challenges of diagnosing precocious or delayed puberty. Studies also explored further the genetic architecture of pathological puberty and identified rare new variants explaining central precocious puberty as well as common variants participating to constitutional delay of growth and puberty. The studies summarized in this chapter underline the future importance of polygenic scores for exploring abnormal puberty.
Basic science research this year illustrates the importance of the regulation of reproductive maturation by energy accessibility. Glutamate transmission in leptin sensitive neurons is required for normal pubertal development and bile acids appear to define a new role for the hepatic-gut-neuroendocrine axis in the control of puberty.
Volume 21
Article tools
My recent searches
My recently viewed abstracts
ESPE Yearbook of Paediatric Endocrinology
ISSN 1662-4009 (Online)
© Bioscientifica 2024 |
Privacy policy |
Cookie settings
BiosciAbstracts
Bioscientifica Abstracts is the gateway to a series of products that provide a permanent, citable record of abstracts for biomedical and life science conferences.
Find out more