ESPE Yearbook of Paediatric Endocrinology

To read the full abstract: Int Health 2018; 10; 66-70This article summarizes the concept of Developmental Origins of Health and Disease (DOHaD) and emphasizes its potential relevance to the marked increase in non-communicable diseases, including Type 2 diabetes, observed in low-resource settings. This is an important topic as the DOHaD concept may be a strong contributing factor to the develop...

To read the full abstract: Lancet Diabetes Endocrinol 2018; 6:69-80The prevalence of T2DM in youth is increasing dramatically worldwide, but the bulk of the increase is expected to take place in Africa, South East Asia and South America. Although genetic factors may seem to be the obvious reason for such geographical differences, a careful analysis of the existing literature suggests that...

To read the full abstract: Lancet Diabetes Endocrinol 2017; 5(8):622-667The Lancet Diabetes and Endocrinology Commission provides a comprehensive, evidence-based review of diabetes in sub-Saharan Africa, one of the most important emerging diseases and markers of the global epidemic of non-communicable diseases. The authors provide a detailed analysis of the significant knowledge gaps in t...

To read the full abstract: Horm Res Paediatr. 2018; Jul 26:1-1As the global burden of non-communicable diseases (NCD) is rising to epidemic levels worldwide, efforts are underway to build capacity for childhood NCDs in low- and middle-income countries (LMICs), including among health care providers in pediatric endocrinology. With increased ability to recognize and diagnose pediatric endocrine conditi...

To read the full abstract: World J Diabetes 2017; 8(9):429-435This is the first paper to describe the clinical presentation and social determinants in youth with diabetes residing and cared for at a single tertiary care center in Ghana that is supported by the International Diabetes Federation’s Life for a Child (LFAC) program. As demonstrated by the ability to conduct and publish this stud...

To read the full abstract: Pediatr Diabetes 2018; 19: (6) 1124In this cross-sectional study performed in Haiti, the authors found that 18% of the children and adolescents with diabetes had signs of retinopathy and that 16% had a cataract. This prevalence is clearly much higher than reported in young patients with diabetes living in high-income countries. Importantly, ocular complications occurred ea...

This GWAS meta-analysis combined data from five well known ethnically diverse cohorts (Framingham Heart Study, Atherosclerosis Risk in Communities Study, Multiethnic Study of Atherosclerosis, Taiwan-Metabochip Study for Cardiovascular Disease, and Singapore Prospective Study) to evaluate glycemic and erythrocytic genetic variants impacting HbA1c in individuals of European, African American, and East Asians ancestry. The study found new and known glycemic and...