Gut flora is shaped by the environment

ey0015.14-5 | Gut flora is shaped by the environment | ESPEYB15

14.5 Environment dominates over host genetics in shaping human gut microbiota

D Rothschild , O Weissbrod , E Barkan , A Kurilshikov , T Korem , D Zeevi , PI Costea , A Godneva , IN Kalka , N Bar

To read the full abstract: Nature 2018;555:210Up to now, it was thought that genetics would play a major role in shaping the gut flora. However, this study, in a cohort of 1,046 healthy Israeli individuals with a well-defined clinical phenotype, suggests that only 2-8% of human microbiome variability is explained by genetics, as compared to 92-98% explained by environmental influences. This...

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ESPE Yearbook of Paediatric Endocrinology

Yearbook of Paediatric Endocrinology 2018

14 Science and Medicine

14.5 Environment dominates over host genetics in shaping human gut microbiota

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