ESPE Yearbook of Paediatric Endocrinology

To read the full abstract: Front Endocrinol (Lausanne). 2018 Apr 6;9:148Pubertal onset and subsequently reproduction result from the awakening of a complex neuroendocrine machinery leading to the acceleration of the gonadotropin-releasing hormone (GnRH) secretion by the hypothalamus. Several neuronal, glial or peripheral factors have been identified as playing a major role in the onset of...