ESPE Yearbook of Paediatric Endocrinology

Nature Digital Medicine 2018;1:39.DOI: 10.1038/s41746-018-0040-6Summary: This prospective observational study evaluated the performance of a diabetic retinopathy diagnostic system (IDx-DR) compared to the gold standard diagnostic for diabetic retinopathy. Nine hundred individuals with diabetes but without a history of diabetic retinopathy were examined. Re...

J Clin Psychiatry 2018;79.DOI: 10.4088/JCP.17m11607Summary: In a population-based prospective cohort study, based on the Taiwan National Health Insurance Research Database, 35,949 adolescents and young adults with attention-deficit/hyperactivity disorder (ADHD) had a higher risk of developing T2DM and had a shorter duration between enrollment and onset of T2DM ...

Diabetes Care 2018;41:1696–1706.doi: 10.2337/dc18-0244URL http://www.ncbi.nlm.nih.gov/pubmed/29941497Summary: In a case control study, age-related differences were compared between youth and adults with impaired glucose tolerance (IGT) or recently diagnosed diabetes. Youth had lower insulin sensitivity, hyperresponsive &#9...

Diabetes Care 2018;41:1717–1725.DOI: 10.2337/dc18-0787http://www.ncbi.nlm.nih.gov/pubmed/29941500Summary: In a randomized, open label clinical trial of 91 adolescents with IGT or new onset T2DM, one-year early interventions with long-acting insulin followed by metformin, or with metformin alone failed to prevent dete...

N Engl J Med 2019; 10.1056/NEJMoa1903822.DOI: 10.1056/NEJMoa1903822http://www.ncbi.nlm.nih.gov/pubmed/31034184Summary: In a double-blind, randomized, phase 3 trial, 135 overweight and obese adolescents, aged 10 to 17 years with T2DM, were randomly assigned to receive subcutaneous liraglutide (up to 1.8 mg per day) or placebo, bot...