ESPE Yearbook of Paediatric Endocrinology

ESPE Yearbook of Paediatric Endocrinology

ISSN 1662-4009 (online)

Published by BioScientifica
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Yearbook of Paediatric Endocrinology 2020

2. Antenatal and Neonatal Endocrinology

Gestational Diabetes Mellitus: Neonatal and Long-term Consequences

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Updates on the Genetics of Neonatal Diabetes Mellitus, Congenital Hyperinsulinism and Glucose Disorders
Table of contents
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Maternal Obesity and Long-Term Infant Consequences

ey0017.2-14 | Gestational Diabetes Mellitus: Neonatal and Long-term Consequences | ESPEYB17

2.14. Gestational diabetes adversely affects pancreatic islet architecture and function in the male rat offspring

P Agarwal , N Brar , TS Morriseau , SM Kereliuk , MA Fonseca , LK Cole , A Jha , B Xiang , KL Hunt , N Seshadri , GM Hatch , CA Doucette , VW Dolinsky

To read the full abstract: Endocrinology. 2019 Aug 1;160(8):1907–1925. PMID: 31237608Gestational diabetes (GDM) is associated with impaired beta-cell function in the offspring and this leads to increased risk of type 2 diabetes mellitus (1). However, the underlying mechanisms are not well understood. GDM exposure may alter islet gene expression and function in the fetus. Impai...
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ey0017.2-15 | Gestational Diabetes Mellitus: Neonatal and Long-term Consequences | ESPEYB17

2.15. Efficacy of fish oil and/or probiotic intervention on the incidence of gestational diabetes mellitus in an at-risk group of overweight and obese women: A randomized, placebo-controlled, double-blind clinical trial

O Pellonpera , K Mokkala , N Houttu , T Vahlberg , E Koivuniemi , K Tertti , T Ronnemaa , K Laitinen

To read the full abstract: Diabetes Care. 2019 Jun;42(6):1009–1017. PMID: 30967436Gestational diabetes mellitus (GDM) is increasing in incidence, affecting approximately 14% of pregnancies. Preventing GDM may significantly improve outcome for both mothers and offspring. The pathogenesis of GDM involves insulin resistance, pancreatic beta-cell failure and an increase in inflamm...
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ey0017.2-16 | Gestational Diabetes Mellitus: Neonatal and Long-term Consequences | ESPEYB17

2.16. Lactational metformin exposure programs offspring white adipose tissue glucose homeostasis and resilience to metabolic stress in a sex-dependent manner

Z Carlson , H Hafner , M Mulcahy , K Bullock , A Zhu , D Bridges , E Bernal-Mizrachi , B Gregg

To read the full abstract: Am J Physiol Endocrinol Metab. 2020 May 1;318(5):E600–E612. doi: 10.1152/ajpendo.00473.2019. Epub 2020 Mar 10. PMID: 32154743The window of lactation is a critical period during which nutritional and environmental exposures may impact lifelong risks of metabolic diseases (such as type 2 diabetes and obesity). Significant organ and tissue development, organ...
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ESPE Yearbook of Paediatric Endocrinology
ISSN 1662-4009 (Online)
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