ESPE Yearbook of Paediatric Endocrinology

Preface: In the puberty field this year, several high impact basic studies highlighted the role of neurotrophic factors and microRNA in GnRH neuron migration and activation around puberty. Fascinating discoveries were made regarding the transcriptome of developing GnRH neurons and testicular cells.This chapter also summarizes new data regarding the genetic architecture of the control of puberty using GWAS studies in boys as well as much awaited data rega...