ISSN 1662-4009 (online)

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Yearbook of Paediatric Endocrinology 2020

9. Oncology and Chronic Disease

Premature Aging, Cardiometabolic Fitness and Cardiovascular Damage

ey0017.9-9 | Premature Aging, Cardiometabolic Fitness and Cardiovascular Damage | ESPEYB17

9.9. Advanced glycation end products and chronic inflammation in adult survivors of childhood leukemia treated with hematopoietic stem cell transplantation

F Felicetti , AS Cento , P Fornengo , M Cassader , R Mastrocola , F D’Ascenzo , F Settanni , A Benso , E Arvat , M Collino , F Fagioli , M Aragno , E Brignardello

To read the full abstract: Pediatr Blood Cancer. 2020 Mar;67(3):e28106. ebrignardello@cittadellasalute.to.itPremature aging has been proposed as a paradigm to explain the early cardiovascular disease (CVD) that affects young-adult childhood cancer survivors (CCS). Protein glycation is recognized as one of the main factors contributing to aging. Advanced glycation end products (AGEs) are a...

ey0017.9-10 | Premature Aging, Cardiometabolic Fitness and Cardiovascular Damage | ESPEYB17

9.10. Childhood leukemia survivors and metabolic response to exercise: A pilot controlled study

C Pegon , E Rochette , N Rouel , B Pereira , E Dore , F Isfan , V Greze , E Merlin , J Kanold , P Duche

To read the full abstract: J Clin Med. 2020 Feb 19;9(2). pii: E562. e_rochette@chu-clermontferrand.frThis 5-month prospective case-control study was designed to evaluate the impairment of metabolic response to exercise in 20 childhood acute leukaemia survivors (CALSs), by the analysis of substrate oxidation during submaximal exercise, in comparison with 20 matched healthy controls.<p cla...

ey0017.9-11 | Premature Aging, Cardiometabolic Fitness and Cardiovascular Damage | ESPEYB17

9.11. Retinal vessel analysis as a novel screening tool to identify childhood acute lymphoblastic leukemia survivors at risk of cardiovascular disease

MS Azanan , S Chandrasekaran , ES Rosli , LL Chua , L Oh , TF Chin , TY Yap , R Rajagopal , R Rajasuriar , T MacGillivray , E Trucco , N Ramli , TA Kamalden , H Ariffin

To read the full abstract: J Pediatr Hematol Oncol. 2020;10.1097/MPH.0000000000001766. doi:10.1097/MPH.0000000000001766 [published online ahead of print, 2020 Feb 28]. taftkamalden@um.edu.myChildhood cancer survivors (CCS) have a markedly increased incidence of early cardiovascular disease (CVD). Changes in retinal vessel diameter are associa...