ESPE Yearbook of Paediatric Endocrinology

Preface: Survival rates of childhood cancer have been steadily improving over the past 3 decades, with 5-year overall survival now approaching 85% in Western countries. These changes have shifted parental and patients’ concerns. While survival was previously the primary concern, the late effects of cancer treatment are now becoming major healthcare issues. Epidemiological studies in childhood cancer survivors (CCS) have shown a significant decrease in male fertility when ...