ESPE Yearbook of Paediatric Endocrinology

ESPE Yearbook of Paediatric Endocrinology

ISSN 1662-4009 (online)

Published by BioScientifica
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Yearbook of Paediatric Endocrinology 2021

13. Global Health for the Paediatric Endocrinologist

Endocrinology

Previous section
Diabetes
Table of contents

ey0018.13-6 | Endocrinology | ESPEYB18

13.6. Tiered healthcare in South Africa exposes deficiencies in management and more patients with infectious etiology of primary adrenal insufficiency

TRP Mofokeng , KCZ Ndlovu , SA Beshyah , IL Ross

PLoS ONE 2020; 15: e0241845. doi: 10.1371/journal.pone.0241845– To determine the etiology, presentation, and available management strategies for primary adrenal insufficiency in South Africa– A 23-question survey was sent to 23,321 physicians. It covered several domains including patient demographics, etiology, presentation, therapy, and barriers to diagnosis and treatment,&...
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ey0018.13-7 | Endocrinology | ESPEYB18

13.7. We all have a role to play: redressing inequities for children living with CAH and other chronic health conditions of childhood in resource-poor settings

K Armstrong , AB Yap , S Chan-Cua , ME Craig , C Cole , V Chi Dung , J Hansen , M Ibrahim , H Nadeem , A Pulungan , J Raza , A Utari , P. Ward

Int. J. Neonatal Screen 2020; 6: 76. doi: 10.3390/ijns6040076– CLAN (Caring and Living as Neighbours) is an Australian non-governmental organisation (NGO) committed to a rights-based approach to optimizing quality of life for children and young people living with CAH and other chronic health conditions in resource-limited settings– This paper used exploratory case study as a method t...
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ey0018.13-8 | Endocrinology | ESPEYB18

13.8. Analysis of the screening results for congenital adrenal hyperplasia involving 7.85 million newborns in China: a systematic review and meta-analysis

Z Li , L Huang , C Du , C Zhang , M Zhang , Y Liang , X Luo

Front Endocrinol 2021; 12:624507. doi: 10.3389/fendo.2021.624507– This systematic review identified 41 Chinese studies totalling 7,853,756 newborns who underwent neonatal CAH screening– The overall incidence of CAH in China was 1/23,024 (95% CI, 1/25,757 to 1/20,815)– Among the CAH patients, the Male:Female ratio was 1.92:1, and 76% presented with salt wasting<p class=...
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ey0018.13-9 | Endocrinology | ESPEYB18

13.9. Health-related quality of life of female patients with congenital adrenal hyperplasia in Malaysia

AA Zainuddin , SR Grover , NA Abdul Ghani , LL Wu , R Rasat , MR Abdul Manaf , K Shamsuddin , ZA Mahdy

Health Qual Life Outcomes 2020; 18: 258. doi: 10.1186/s12955-020-01515-9– The authors compared the quality of life (QOL) in 59 patients with CAH raised as females to 57 female patients with diabetes– Patients with CAH included 12 children, 29 adolescents and 18 adults– They found that the health-related QOL of female patients with CAH was similar to the QOL of patients wi...
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ey0018.13-10 | Endocrinology | ESPEYB18

13.10. A multicenter cross-sectional study of Malaysian females with congenital adrenal hyperplasia: their body image and their perspectives on feminizing surgery

AM Zainuddin , SR Grover , CH Soon , NA Abdul Ghani , ZA Mahdy , MR Abdul Manaf , K Shamsuddin

J Pediatr Adolesc Gynecol 2020 Oct;33(5):477-483. doi: 10.1016/j.jpag.2020.04.008– Body image and perceptions around feminizing genitoplasty were assessed in 59 children, adolescents and adults with CAH (raised and identifying as females) and their parents– Participants were more concerned with their overall appearance than with appearance of genitalia– A younger age and ...
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ey0018.13-11 | Endocrinology | ESPEYB18

13.11. Clinical characteristics of 46,XX males with congenital adrenal hyperplasia

S Savaş-Erdeve , Z Aycan , S Cetinkaya , AP Ozturk , F Bas , S Poyrazoglu , F Darendeliler , E Ozsu , Z Sıklar , M Demiral , E Unal , M Nuri Ozbek , F Gurbuz , B Yuksel , O Evliyaoglu , N Akyurek , M Berberoglu

J Clin Res Pediatr Endocrinol 2020 Dec 30.doi: 10.4274/jcrpe.galenos.2020.2020.0216– The characteristics of 44 patients with 46,XX congenital adrenal hyperplasia (CAH) who were raised as males were described– 15/44 (34%) were diagnosed before 2 years of age– The median final height was 149.2 (range 133–172) cmThis paper discusses an important ...
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ey0018.13-12 | Endocrinology | ESPEYB18

13.12. Trends of congenital hypothyroidism and inborn errors of metabolism in Pakistan

S Mansoor

Orphanet J Rare Dis 2020 15:321. doi: 10.1186/s13023-020-01602-6– In Pakistan, there is presently no systematic neonatal screening for congenital hypothyroidism and other inborn errors of metabolism– A review of published articles was performed to calculate a probable estimate of the disease burden in the Pakistani populationMansoor highlights the fact t...
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ey0018.13-13 | Endocrinology | ESPEYB18

13.13. Aetiologies and clinical patterns of hypopituitarism in Sudanese children

SS Hassan , R Mukhwana , S Musa , AAB Ibrahim , O Babiker , MA Abdullah

Sudan J Paediatr 2021;21:53–60. doi: 10.24911/SJP.106-1588448825– This paper describes the characteristics of 156 children and adolescents with hypopituitarism from 2 hospitals in Sudan– Congenital causes (86.5%) were more prevalent than acquired causes (13.5%)– Consanguinity was found in 77.8% of patients overall and 91% of patients with congenital aetiologies. The...
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ey0018.13-14 | Endocrinology | ESPEYB18

13.14. Effect on mortality of increasing the cutoff blood glucose concentration for initiating hypoglycaemia treatment in severely sick children aged 1 month to 5 years in Malawi (SugarFACT): a pragmatic, randomised controlled trial

T Baker , F Ngwalangwa , H Masanjala , Q Dube , J Langton , G Marrone , H Hildenwall

Lancet Glob Health 2020; 8: e1546–54. doi: 10.1016/S2214-109X(20)30388-0– Hypoglycemia is associated with increased mortality in severely sick children. WHO recommends treatment of hypoglycemia for a blood glucose < 2.5 mmol/l– The authors hypothesized that increasing the threshold for the treatment of hypoglycemia from 2.5 to 5 mmol/l would reduce all cause in-hos...
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ey0018.13-15 | Endocrinology | ESPEYB18

13.15. Height and body-mass index trajectories of school-aged children and adolescents from 1985 to 2019 in 200 countries and territories: a pooled analysis of 2181 population-based studies with 65 million participants

Lancet 2020; 396: 1511–24. doi: 10.1016/S0140-6736(20)31859-6– This study aimed to estimate trends in mean height and mean body-mass index (BMI) between 1985 to 2019 for children and adolescents aged 5–19 years– There was a difference of ≥ 20 cm in mean height and of 9–10 kg/m2 in mean BMI in 19-year-old adolescents between countries with the...
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ey0018.13-16 | Endocrinology | ESPEYB18

13.16. Maternal stature, maternal education and child growth in Pakistan: a cross-sectional study

N Javid , C Pu

AIMS Public Health 2020; 7(2): 380–392. doi: 10.3934/publichealth.2020032– Pakistan has a significantly higher prevalence of stunted children under 5 years old compared with other countries of the same income level. Stunting is more frequent in children of shorter compared to taller mothers– The authors hypothesized that higher maternal education, a modifiable factor, i...
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ESPE Yearbook of Paediatric Endocrinology
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