ESPEYB18 3. Thyroid Congenital hypothyroidism (3 abstracts)
3.8. Congenital hypothyroidism: A 2020-2021 consensus guidelines update-An ENDO-European Reference Network initiative endorsed by the European Society for Pediatric Endocrinology and the European Society for Endocrinology
van Trotsenburg P , Stoupa A , Léger J , Rohrer T , Peters C , Fugazzola L , Cassio A , Heinrichs C , Beauloye V , Pohlenz J , Rodien P , Coutant R , Szinnai G , Murray P , Bartés B , Luton D , Salerno M , de Sanctis L , Vigone M , Krude H , Persani L & Polak M
Thyroid. 2021:387–419. doi: 10.1089/thy.2020.0333.
These updated ENDO-European Reference Network (ENDO-ERN), European Society for Paediatric Endocrinology (ESPE) and European Society for Endocrinology (ESE) guidelines for congenital hypothyroidism will serve as comprehensive review of the literature providing recommendations to all aspects of the disease.
The first Consensus Guidelines for congenital hypothyroidism of ESPE were published in 2014 [1]. This revised version of the guidelines was realized by a panel of paediatric and adult endocrinologists, obstetricians, and a representative of patient organisations. They give an update on all recommendations in the light of new evidence and knowledge from the literature between 2013 and 2020 according to the GRADE (grading of recommendations, assessment, development, and evaluation) system. The evidence section for each recommendation provide detailed discussion of the current available literature and questions that remain and need further clinical research. The main chapters comprise neonatal screening, diagnostic criteria, substitutive treatment, outcome, genetics, and antenatal diagnosis and cover all aspects of primary congenital hypothyroidism. Major innovations are the integration of recommendations for central congenital hypothyroidism and a comprehensive update on known and new genetic forms of congenital hypothyroidism.
Reference: 1. Léger J, Olivieri A, Donaldson M, Torresani T, Krude H, van Vliet G, Polak M, Butler G; ESPE-PES-SLEP-JSPE-APEG-APPES-ISPAE; Congenital Hypothyroidism Consensus Conference Group. European Society for Paediatric Endocrinology consensus guidelines on screening, diagnosis, and management of congenital hypothyroidism. J Clin Endocrinol Metab. 2014;99:363–84. doi: 10.1210/jc.2013-1891.
Volume 18
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ESPE Yearbook of Paediatric Endocrinology
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