ESPE Yearbook of Paediatric Endocrinology

Journal of the American Heart Association 2021;10(24):e021701. doi: 10.1161/JAHA.121.021701Brief Summary: This population-based birth cohort study identified an association between childhood abuse and higher BMI at age 18 and 25 years, and also hyperinsulinemia and other markers of the MetS at age 25.Comment: Previous studies reported that about one-third of adult candi...

Biomedical and Environmental Sciences, 2021, 34(8): 623–631 doi: 10.3967/bes2021.086Brief Summary: This cross-sectional study identified associations between serum ferritin levels with dyslipidemia and the MetS in both adult men and women. In addition, significant associations were found for ferritin levels with the risks of insulin resistance, prediabetes and T2DM in women.<p class="abs...

Cell metabolism 2021;33(12):2316-28. doi: 10.1016/j.cmet.2021.09.004Brief Summary: This paper reviews the links between fructose consumption and health, and the mechanisms by which fructose may damage health.Comment: Fructose is a plant-derived monosaccharide. Its natural form is found in certain fruits and vegetables. High-fructose corn syrup (HFCS) is a liquid fruc...

Nat Rev Endocrinol 2021;17(8):484-95. doi: 10.1038/s41574-021-00507-zBrief Summary: This article reviews the results of clinical trials for modulators of glucagon-like peptide-1 (GLP1) activity, insulin-sensitizing thiazolidinediones, and inhibitors of the sodium-glucose cotransporter 2 (SGLT2) for the treatment of NAFLD and type 2 diabetes mellitus.Comment: NAFLD ha...

Cell metabolism 2022;34(2):329-45.e8. doi: 10.1016/j.cmet.2021.12.016Brief Summary: In a mouse model, time of exercise during the day was found to determine the magnitude and type of metabolic response. Different tissues responded to exercise at different times of the day.Comment: Exercise is considered a vital intervention in the prevention and treatment of individu...