ESPE Yearbook of Paediatric Endocrinology

ESPE Yearbook of Paediatric Endocrinology

ISSN 1662-4009 (online)

Published by BioScientifica
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Yearbook of Paediatric Endocrinology 2022

9. Oncology and Chronic Disease

Fertility issues and reproductive outcomes in childhood cancer survivors

Previous section
Adrenal function after cancer treatment
Table of contents
Next section
Bone health in chronic disease

ey0019.9-6 | Fertility issues and reproductive outcomes in childhood cancer survivors | ESPEYB19

9.6. Serum anti-mullerian hormone levels and risk of premature ovarian insufficiency in female childhood cancer survivors: systematic review and network meta-analysis

Torella M. , Riemma G. , De Franciscis P. , L Verde M. , Colacurci N.

gaetano.riemma@unicampania.it Cancers 2021, 13, 6331. PMID: 34944951.Brief Summary: This systematic review and meta-analysis examined the value of anti-Müllerian hormone (AMH) to predict premature ovarian failure (POI) in childhood cancer survivors (CCSs), compared to the general population.The potential toxic effect of alkylating agents and body irradiation on female...
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ey0019.9-7 | Fertility issues and reproductive outcomes in childhood cancer survivors | ESPEYB19

9.7. Fertility status among long-term childhood acute lymphoblastic leukaemia survivors enrolled between 1971 and 1998 in EORTC CLG studies: results of the 58 late adverse effects study

Rossi G. , Kicinski M. , Suciu S. , Vandecruys E. , Plat G. , Uyttebroeck A. , Paillard C. , Barbati M. , Dresse M.F. , Simon P. , Minckes O. , Pluchart C. , Ferster A. , Freycon C. , Millot F. , van der Werfften Bosch J. , Chantrain C. , Paulus R. , de Rojas T. , de Schaetzen G. , Rohrlich P. , Benoit Y. , Piette C.

On behalf of the European Organisation for Research and Treatment of Cancer (EORTC) Children’s Leukemia Group (CLG)caroline.piette@chuliege.be Human Reproduction, 2022; 37: 44–53. PMID: 34788455.Brief Summary: This case-control study evaluated fertility status in childhood acute lymphoblastic leukaemia (ALL) survivors enrolled in the European Organisation for Research and Treatment of Ca...
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ey0019.9-8 | Fertility issues and reproductive outcomes in childhood cancer survivors | ESPEYB19

9.8. Temporal changes in the probability of live birth among female survivors of childhood cancer: a population-based adult life after childhood cancer in Scandinavia (ALiCCS) study in five Nordic countries

de Fine Licht S. , Rugbjerg K. , Andersen E.W. , Nielsen T.T. , Nyboe Norsker F. , Kenborg L. , Holmqvist A.S. , Madanat-Harjuoja L.M. , Tryggvadottir L. , Stovall M. , Wesenberg F. , Hjorth L. , Hasle H. , Winther J.F.

Adult Life After Childhood Cancer in Scandinavia Study Groupkenborg@cancer.dk Cancer 2021; 127: 3881-3892. PMID: 34297360.Brief Summary: This register-based cohort study analysed the likelihood of live birth among female childhood cancer survivors (CCSs) diagnosed in between 1943 and 2006, in comparison with the general population. The prevalence of first live birth was lower in CCSs compared to matched con...
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ey0019.9-9 | Fertility issues and reproductive outcomes in childhood cancer survivors | ESPEYB19

9.9. Parenthood among men diagnosed with cancer in childhood and early adulthood: trends over time in a Danish national cohort

Sylvest R. , Vassard D. , Schmidt L. , Schmiegelow K. , Macklon K.T. , Forman J.L. , Pinborg A.

randi.lykke-sylvest@regionh.dk Human Reproduction, Vol.36, No.9, pp. 2576–2586, 2021. PMID: 34166497.Brief Summary: This Danish register-based cohort study investigated the rate of fatherhood among 9,353 men diagnosed with cancer during childhood or early adulthood (CSs), compared with 1,386,493 age-matched males without cancer. CSs became fathers slightly less frequently than controls (36...
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ey0019.9-10 | Fertility issues and reproductive outcomes in childhood cancer survivors | ESPEYB19

9.10. In male Hodgkin lymphoma patients, impaired fertility may be improved by non-gonadotoxic therapy

Laddaga F.E. , Masciopinto P. , Nardelli C. , Vacca M.P. , Masciandaro P. , Arcuti E. , Cicinelli E. , Specchia G. , Musto P. , Gaudio F.

fragaudio@alice.it British Journal of Haematology, 2022, 196, 110–115. PMID: 34462914.Brief Summary: This prospective single-centre study evaluated fertility in men diagnosed with Hodgkin lymphoma (HL) by sperm analysis, in order to identify clinical and biological characteristics correlated with fertility status. Only 28% of men showed normal sperm analysis.Previous studies in ...
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ey0019.9-11 | Fertility issues and reproductive outcomes in childhood cancer survivors | ESPEYB19

9.11. Assessment of the architecture and integrity of frozen-thawed testicular tissue from (pre)pubertal boys with cancer

Rives-Feraille A. , Liard A. , Bubenheim M. , Barbotin A.L. , Giscard d'Estaing S. , Mirallie S. , Ancelle A. , Roux C. , Brugnon F. , Greze V. , Daudin M. , Willson-Plat G. , Dubois R. , Sibert L. , Schneider P. , Rives N.

nathalie.rives@chu-rouen.fr Andrology. 2022; 10: 279–290. PMID: 34628730.Brief Summary: This multicentric prospective study performed an accurate evaluation of testicular tissue after frozen-thawing to investigate if this testicular tissue freezing (TTF) alters testicular architecture and integrity in pre-pubertal and pubertal boys with cancer. Promising histological outcomes were found. ...
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ey0019.9-12 | Fertility issues and reproductive outcomes in childhood cancer survivors | ESPEYB19

9.12. Pregnancy and pregnancy outcomes after hematopoietic stem cell transplantation in childhood: a cross-sectional survey of the EBMT pediatric diseases working party

T Diesch-Furlanetto , A Rovo , JE Galimard , G Szinnai , A Dalissier , P Sedlacek , I Bodova , VK Roussou , BE Gibson , X Poire , F Fagioli , H Pichler , M Faraci , FG Gumy-Pause , JH Dalle , A Balduzzi , P Bader , S Corbacioglu

tamara.diesch@ukbb.ch.Hum Reprod. 2021; 36: 2871-82. PMID: 34529796.Brief Summary: This retrospective study of the European Society for Blood and Marrow Transplantation (EBMT) registry describes the natural or assisted conceptions and their outcomes in patients <18-year-old at their first transplantation who received hematopoietic stem cell transplantation (HSCT) between 1995 and 2016. <p class=...
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ey0019.9-13 | Fertility issues and reproductive outcomes in childhood cancer survivors | ESPEYB19

9.13. Serum anti-Mullerian hormone as a marker of ovarian reserve after cancer treatment and/or hematopoietic stem cell transplantation in childhood: proposal for a systematic approach to gonadal assessment

S Molinari , F Parissone , V Evasi , Lorenzo P De , MG Valsecchi , S Cesaro , D Fraschini , R Sangalli , G Cacace , A Biondi , A Balduzzi , A Cattoni

s.molinari3@campus.unimib.it Eur J Endocrinol. 2021; 185: 717-728. PMID: 34519276.Brief Summary: This retrospective study, involving two Italian centers, enrolled post-pubertal female patients who had been treated with gonadotoxic therapies for hematological malignancies and/or hematopoietic stem cell transplantation (HSCT) before the age of 18 years. Several studies have r...
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ey0019.9-14 | Fertility issues and reproductive outcomes in childhood cancer survivors | ESPEYB19

9.14. Effect of Genetic Variation in CYP450 on gonadal impairment in a European cohort of female childhood cancer survivors, based on a candidate gene approach: results from the PanCareLIFE study

der Perk MEM van , L Broer , Y Yasui , LL Robison , MM Hudson , JSE Laven , der Pal HJ van , WJE Tissing , B Versluys , D Bresters , GJL Kaspers , Vries ACH de , CB Lambalk , A Overbeek , JJ Loonen , CCM Beerendonk , J Byrne , C Berger , E Clemens , U Dirksen , Winther J Falck , SD Fossa , D Grabow , M Muraca , M Kaiser , T Kepak , J Kruseova , D Modan-Moses , C Spix , O Zolk , P Kaatsch , JH Krijthe , LCM Kremer , RJ Brooke , JL Baedke , RHN van Schaik , JN van den Anker , AG Uitterlinden , AME Bos , FE van Leeuwen , E van Dulmen-den Broeder , ALF van der Kooi , MM van den Heuvel-Eibrink

On Behalf Of The PanCareLIFE Consortium. m.e.m.vanderperk@prinsesmaximacentrum.nl Cancers (Basel). 2021; 13: 4598. PMID: 34572825.Brief Summary: This cohort study of female childhood cancer survivors (CCS) identified associations between specific nucleotide polymorphisms (SNP) in cytochrome P450 (CYP450) enzymes, which metabolize alkylating agents (AA), and variability in AA-induced o...
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ESPE Yearbook of Paediatric Endocrinology
ISSN 1662-4009 (Online)
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