ISSN 1662-4009 (online)

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Yearbook of Paediatric Endocrinology 2023

ey0020.10-9 | Metabolic Syndrome | ESPEYB20

10.9. The association of metabolic syndrome status with sensorineural hearing loss in pediatric obese patients

O Ozdemir , A Ucar , AD Cakir , E Misir , O Yigit

Brief summary: This study assessed the relation between the metabolic syndrome (MetS) and sensorineural hearing loss in children with obesity. Children with MetS were shown to have subclinical hearing loss compared to those without MetS.Comment: Associations between obesity and hearing loss have been reported in several adult studies.1 However, similar studies in adolescents have yielded conflicting results. The present study aimed to address ...

ey0020.10-10 | Metabolic Syndrome | ESPEYB20

10.10. Iron metabolism and ferroptosis in type 2 diabetes mellitus and complications: mechanisms and therapeutic opportunities

R Miao , X Fang , Y Zhang , J Wei , Y Zhang , J Tian

Brief summary: This paper reviews the associations between cellular iron, ferroptosis and diabetes. It also explores the therapeutic potential of ferroptosis inhibitors in the treatment of diabetic complications.Comment: Ferroptosis is a form of regulated cell death that is characterized by the decreased capacity of antioxidants and the accumulation of lipid reactive oxygen species (ROS).1 This, in turn, causes oxidative damage to cell membran...