New Concerns

6.9. Leukocyte telomere length in children with congenital adrenal hyperplasia

C Raftopoulou , O Abawi , G Sommer , M Binou , G Paltoglou , CE Fluck , ELT van den Akker , E Charmandari

Brief summary: This prospective observational cohort study determined leukocyte telomere length (LTL) in 76 patients with genetically confirmed CAH (83% classic CAH). LTL was shorter in patients with classic vs nonclassic CAH, in overtreated than in optimally treated patients, and patients receiving prednisolone compared with hydrocortisone.Telomeres are tandem repeats of a noncoding hexameric nucleotide sequence (5′-TTAGGG-3′) located at the...

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ey0020.6-10 | New Concerns | ESPEYB20

6.10. Body composition in children and adolescents with non-classic congenital adrenal hyperplasia and the risk for components of metabolic syndrome: An observational study

A Ben Simon , A Brener , A Segev-Becker , M Yackobovitch-Gavan , A Uretzky , A Schachter Davidov , A Alaev , A Oren , O Eyal , N Weintrob , Y Lebenthal

Brief summary: This retrospective case-control observational study assessed body composition of children with non-classic congenital adrenal hyperplasia (NCCAH) using bioelectrical impedance analysis (BIA). It showed that children with NCCAH have an imbalance between muscle and fat tissues compared with control subjects, which may place them at increased risk for early-onset cardiometabolic morbidity.Non-classic congenital adrenal hyperplasia (NCCAH) is ...

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ESPE Yearbook of Paediatric Endocrinology

Yearbook of Paediatric Endocrinology 2023

6. Adrenals

6.9. Leukocyte telomere length in children with congenital adrenal hyperplasia

6.10. Body composition in children and adolescents with non-classic congenital adrenal hyperplasia and the risk for components of metabolic syndrome: An observational study

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