ISSN 1662-4009 (online)

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Yearbook of Paediatric Endocrinology 2023

6. Adrenals

New Paradigms

ey0020.6-12 | New Paradigms | ESPEYB20

6.12. Regulatory mechanisms of microRNAs in endocrine disorders and their therapeutic potential

SJ Ledesma-Pacheco , AG Uriostegui-Pena , E Rodriguez-Jacinto , E Gomez-Hernandez , C Estrada-Meza , A Banerjee , S Pathak , LM Ruiz-Manriquez , AK Duttaroy , S Paul

Brief summary: This study summarises the involvement of specific miRNAs in diabetes mellitus, thyroid diseases, osteoporosis, pituitary tumours, Cushing’s disease, adrenal insufficiency and multiple endocrine neoplasia’s. Furthermore, the potential of miRNA as candidates for developing novel diagnostic and therapeutic tools is also discussed.Endocrine disorders are common worldwide and represent a considerable public health problem due to long ...