Adrenal Function and Cancer Treatment

ey0020.7-11 | Adrenal Function and Cancer Treatment | ESPEYB20

7.11. Cortisol response in children with cancer and fever during chemotherapy: A prospective, observational study using random serum cortisol levels

A Boekstegers , H Schmidt , M Kurzay , T Vallee , E Jung , I Dubinski , R Maxwell , I Schmid

Brief summary: This single-centre retrospective study evaluated cortisol responses during febrile episodes in children with cancer. Low cortisol responses were common and were unrelated to current steroid therapy.Random serum cortisol and ACTH were measured in 75 children and adolescents with cancer while admitted for fever during chemotherapy; 47/75 patients received glucocorticoids as part of their treatment (steroid group). A low cortisol response (LC...

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ey0020.7-12 | Adrenal Function and Cancer Treatment | ESPEYB20

7.12. The assessment of the hypothalamic-pituitary-adrenal axis after oncological treatment in pediatric patients with acute lymphoblastic leukemia

B Hull , A Wędrychowicz , M Ossowska , A Furtak , J Badacz , S Skoczeń , JB Starzyk

Brief summary: Chemotherapy, radiotherapy and corticosteroids used to treat acute lymphoblastic leukemia (ALL) can have endocrine side-effects, such as adrenal insufficiency (AI). This cross-sectional single-centre study aimed to assess AI frequency after completion of ALL therapy, by comparison to healthy controls matched for age and sex, and to identify biomarkers of adrenal function and reserve.Study patients were at least 16 months post-completion of...

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ESPE Yearbook of Paediatric Endocrinology

Yearbook of Paediatric Endocrinology 2023

7. Oncology and Chronic Disease

7.11. Cortisol response in children with cancer and fever during chemotherapy: A prospective, observational study using random serum cortisol levels

7.12. The assessment of the hypothalamic-pituitary-adrenal axis after oncological treatment in pediatric patients with acute lymphoblastic leukemia

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