ISSN 1662-4009 (online)

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Yearbook of Paediatric Endocrinology 2023

7. Oncology and Chronic Disease

Long-Term Surveillance for Endocrine Complications in Childhood Cancer Survivors

ey0020.7-13 | Long-Term Surveillance for Endocrine Complications in Childhood Cancer Survivors | ESPEYB20

7.13. Management of childhood cancer survivors at risk for thyroid function abnormalities: A Delphi study

JJG Welch , B Ames , LE Cohen , E Gaufberg , MM Hudson , PC Nathan , L Nekhlyudov , TI Yock , W Chemaitilly , LB Kenney

Brief summary: This study used a Delphi approach to generate consensus guidelines for screening of asymptomatic childhood cancer survivors for thyroid dysfunction and recommendations for the management of abnormal thyroid screening results.A Delphi panel of 40 clinical experts (oncologists, endocrinologists, and primary care physicians) participated in three rounds of anonymous questionnaires, formatted as clinical scenarios. Consensus was defined by agr...

ey0020.7-14 | Long-Term Surveillance for Endocrine Complications in Childhood Cancer Survivors | ESPEYB20

7.14. Hypothalamic-pituitary and other endocrine surveillance among childhood cancer survivors

L van Iersel , RL Mulder , C Denzer , LE Cohen , HA Spoudeas , LR Meacham , E Sugden , AYN Schouten-van Meeteren , EW Hoving , RJ Packer , GT Armstrong , S Mostoufi-Moab , AM Stades , D van Vuurden , GO Janssens , C Thomas-Teinturier , RD Murray , N Di Iorgi , SJCMM Neggers , J Thompson , AA Toogood , H Gleeson , C Follin , E Bardi , L Torno , B Patterson , V Morsellino , G Sommer , SC Clement , D Srivastava , CE Kiserud , A Fernandez , K Scheinemann , S Raman , KCJ Yuen , WH Wallace , LS Constine , R Skinner , MM Hudson , LCM Kremer , W Chemaitilly , HM van Santen

Brief summary: In this extensive and updated review, the International Late Effects of Childhood Cancer Guideline Harmonization Group (IGHG) report expert consensus-based guidelines that harmonize recommendations for surveillance of endocrine disorders in childhood cancer survivors.This interdisciplinary panel of 42 international experts formulated new surveillance recommendations for hypothalamic–pituitary (HP) dysfunction. Existing IGHG surveillan...

ey0020.7-15 | Long-Term Surveillance for Endocrine Complications in Childhood Cancer Survivors | ESPEYB20

7.15. Frailty and sarcopenia within the earliest national Dutch childhood cancer survivor cohort (DCCSS-LATER): a cross-sectional study

JE van Atteveld , DTC de Winter , VG Pluimakers , M Fiocco , RAJ Nievelstein , MGG Hobbelink , LCM Kremer , MA Grootenhuis , H Maurice-Stam , WJE Tissing , ACH de Vries , JJ Loonen , E van Dulmen-den Broeder , HJH van der Pal , SMF Pluijm , M van der Heiden-van der Loo , AB Versluijs , M Louwerens , D Bresters , HM van Santen , I Hoefer , SAA van den Berg , J den Hartogh , JHJ Hoeijmakers , SJCMM Neggers , MM van den Heuvel-Eibrink , Dutch LATER study group

Brief summary: This cross-sectional study explored the risk factors for pre-frailty, frailty, and sarcopenia in a cohort of Dutch childhood cancer survivors diagnosed between 1963 and 2001.Frailty was defined as the presence of at least two (pre-frailty) or three (frailty) of the following criteria: low appendicular lean mass (low percentage of lean tissue in the limbs assessed by dual-energy X-ray absorptiometry, DXA), low muscle strength (measured with...