ESPE Yearbook of Paediatric Endocrinology

ESPE Yearbook of Paediatric Endocrinology

ISSN 1662-4009 (online)

Published by BioScientifica
Previous issue | Volume 21 | ESPEYB21

Yearbook of Paediatric Endocrinology 2024

14. The Year in Science and Medicine

Steroid Hormones from Basics to Clinic

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ey0021.14-9 | Steroid Hormones from Basics to Clinic | ESPEYB21

14.9. Sex differences orchestrated by androgens at single-cell resolution

Li Fei , Xing Xudong , Jin Qiqi , Wang Xiang-Ming , Dai Pengfei , Han Ming , Shi Huili , Zhang Ze , Shao Xianlong , Peng Yunyi , Zhu Yiqin , Xu Jiayi , Li Dan , Chen Yu , Wu Wei , Wang Qiao , Yu Chen , Chen Luonan , Bai Fan , Gao Dong

Brief Summary:This study assembled a single-cell transcriptomic atlas representing over 2.3 million cells from 17 tissues in mice. Investigations of the scRNA-seq data focussed on effects of sex and androgens on the molecular programs and cellular populations in female and male mice as well as male androgen-deprived, and female androgen-treated mice. Data were then used to gain novel molecular insight into sex-related human disorders as available in the UK Biobank study.<p...
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ESPE Yearbook of Paediatric Endocrinology
ISSN 1662-4009 (Online)
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