ESPE Yearbook of Paediatric Endocrinology

In Brief: These authors investigated patients referred to the UK National Prion Clinic (NPC) for suspected prion diseases. They identified 8 individuals with a history of receiving treatment with cadaveric pituitary-derived growth hormone (c-hGH) and referred to, or reviewed by, the NPC between 2017 and 2022. None had a diagnosis of iatrogenic Creutzfeldt–Jakob disease (CJD) (on the basis of clinical presentation, neuroimaging and biomarkers and, in two cases, by postmort...

In Brief This systematic review collated evidence from prospective cohort studies (PCS) with at least 6 months follow-up and randomized clinical trials (RCTs) to assess the influence of 100% fruit juice on body weight in children and adults. 100% fruit juice intake was associated with higher BMI gain among children and with higher weight gain in adults.In children, 17 PCS (total 45,851 children) and no RCTs were identified. Each additional serving per da...

In Brief: The authors highlight recent data published by the UK Office for Health Improvement and Disparities (OHID) on estimated excess mortality in England, overall and by age, ethnicity, region and cause. Age-standardised mortality was higher than expected during June 2022 to 30th June 2023. Particular causes of death showed excess mortality: cardiovascular diseases (12% relative excess), heart failure (20%), ischaemic heart diseases (15%), liver diseases (19%), acute respi...

In Brief: The authors perform a population intervention effects analysis of 33 longitudinal cohorts (total 83 671 children, 662 763 measurements), from 15 low- and middle-income counties (LMICs). They estimate that improving maternal anthropometry and child condition at birth would increase population mean length-for-age z-scores by up to 0.40 and weight-for-length z -scores by up to 0.15 by 24 months of age.This is 1 of 3 full articles publishe...