ISSN 1662-4009 (online)

Previous issue | Volume 21 | ESPEYB21

Yearbook of Paediatric Endocrinology 2024

2. Antenatal and Neonatal Endocrinology

Important Associations with Growth

ey0021.2-9 | Important Associations with Growth | ESPEYB21

2.9. The associations between maternal and fetal exposure to endocrine- disrupting chemicals (EDC) and asymmetric fetal growth restriction: a prospective cohort study

S Hong , BS Kang , O Kim , S Won , HS Kim , JH Wie , JE Shin , SK Choi , YS Jo , YH Kim , M Yang , H Kang , D-W Lee , IY Park , JS Park , HS Ko

Brief Summary: This prospective cohort study of 146 mother-neonate pairs determined fetal-maternal exposure to EDCs from October 2021 – October 2022 and examined their associations with fetal growth parameters. Fetal exposure to bisphenol-A (BPA) showed a linear association with asymmetric fetal growth patterns.Their definition of fetal growth restriction (FGR) when assessed by transabdominal ultrasonography at 38.3 weeks gestational age was a fetal...

ey0021.2-10 | Important Associations with Growth | ESPEYB21

2.10. Leptin and adiposity measures from birth to later childhood: Findings from the Hyperglycemia and Adverse Pregnancy Outcomes (HAPO) Follow-Up Study

S DeLacey , M Gurra , J Arzu , LP Lowe , WL Lowe , DM Scholtens , JL Josefson

Brief Summary: This study was based on the HAPO prospective birth cohort, which has previously generated several publications on maternal gestational diabetes in relation to neonatal anthropometry and childhood glucose metabolism1,2. It examined if cord blood leptin was positively associated with peripubertal obesity and adiposity, and if this relationship was dependent on maternal BMI, hyperglycemia and/or other maternal factors.This is an im...

ey0021.2-11 | Important Associations with Growth | ESPEYB21

2.11. Cord Blood Proteomic Profiles, Birth Weight, and Early Life Growth Trajectories

T Van Pee , DS Martens , R Alfano , L Engelen , H Sleurs , L Rasking , M Plusquin , TS Nawrot

Brief Summary: This prospective singleton birth cohort (N=288, 43.4% male) from Flanders, Belgium, was a subset of a larger longitudinal cohort (ENVIRONAGE). The authors used a targeted proteomic panel to measure 386 inflammatory-related proteins in cord blood and examined their associations with birth weight (BW), birth weight ratio (BWR - BW divided by the median BW for gestational age for sex and parity), and rapid infant weight gain (defined as [weight z score at 12 m minu...