ISSN 1662-4009 (online)

Previous issue | Volume 21 | ESPEYB21

Yearbook of Paediatric Endocrinology 2024

6. Differences of Sexual Development (DSD) and Gender Incongruence (GI)

Impact of Masculinizing Hormone Treatment on Fertility

ey0021.6-13 | Impact of Masculinizing Hormone Treatment on Fertility | ESPEYB21

6.13. One-third of amenorrheic transmasculine people on testosterone ovulate

JD Asseler , JS Del Valle , Sousa Lopes SM Chuva de , MO Verhoeven , M Goddijn , JAF Huirne , NM van Mello

Brief Summary: This study analyzed ovariectomy samples from 52 transmasculine individuals who had been using testosterone for >1 year (median 32, IQR 27–39 months) with serum concentrations in the male reference range. In one third (16/52) of the cohort, histological signs of recent ovulatory activity were observed, including the presence of ovulatory follicles, corpus luteum and corpus albicans. This was similar in the subgroup of 15 individuals who had previously us...