ISSN 1662-4009 (online)

ey0021.13-5 | Diabetes and Diabetes Technology | ESPEYB21

13.5. Patient-led innovation and global health justice: Open-source digital health technology for type 1 diabetes care

B Jansky , T Hendl , AZ Nocanda

Brief Summary: This article evaluates the social conditions and global inequalities that shape patient-led innovation in the context of type 1 diabetes (T1D). The multidisciplinary team used an empirical sociological approach combined with normative ethical analyses. They conclude that open-source, patient-led innovation should be developed with a proactive strategy primarily targeting groups experiencing inequalities in access to health services.The acc...

ey0017.15-3 | (1) | ESPEYB17

15.3. An association between maternal weight change in the year before pregnancy and infant birth weight: ELFE, a French national birth cohort study

M Lecorguille , M Jacota , B de Lauzon-Guillain , A Forhan , M Cheminat , MA Charles , B Heude

To read the full abstract: PLoS Med. 2019 Aug 20;16(8):e1002871. doi: 10.1371/journal.pmed.1002871.Women (n =16,395; 26% overweight or obese) from the ELFE French national birth cohort were categorised into 3 groups by self-reported weight change during the year before pregnancy: weight loss >5 kg; stable weight; and weight gain >5 kg.Among women with B...

ey0021.13-7 | Endocrinology | ESPEYB21

13.7. Vitamin D supplements for fracture prevention in schoolchildren in Mongolia: analysis of secondary outcomes from a multicentre, double-blind, randomised, placebo-controlled trial

D Ganmaa , P Khudyakov , U Buyanjargal , E Tserenkhuu , S Erdenenbaatar , CE Achtai , N Yansanjav , B Delgererekh , M Ankhbat , E Tsendjav , B Ochirbat , B Jargalsaikhan , D Enkhmaa , AR Martineau

Brief Summary: This multicenter, double-blind, randomized, placebo-controlled trial evaluated the effects of vitamin D supplementation (14,000 IU D3 weekly for 3 years) on fracture risk and other bone health indicators in 8,851 schoolchildren aged 6–13 years in 18 public schools in Mongolia, where vitamin D deficiency is highly prevalent with a high fracture burden.Vitamin D3 doses were given during weekly face-to-face visits in schools. Families co...

ey0018.10-2 | (1) | ESPEYB18

10.2. Impact of lockdown in COVID-19 on glycemic control in patients with type 1 diabetes mellitus

A Verma , R Rajput , S Verma , VKB Balania , B Jangra

Diabetes Metab Syndr. 2020;14(5):1213–1216. doi: 10.1016/j.dsx.2020.07.016In this small cross-sectional study on 52 pediactric patients with T1D, a structured questionnaire was administered on follow up within 15 days after lockdown during the COVID-19 pandemic. Of these 52 patients, 36.5% had hyperglycemic and 15.3% had hypoglycemic episodes. Insulin dose was missed in 26.9%, gluco...

ey0019.8-3 | New Mechanisms | ESPEYB19

8.3. DNA methylation signatures in human neonatal blood following maternal antenatal corticosteroid treatment

B Kim , S Sasaki , K Murphy , SG Matthews

Transl Psychiatry. 2022; 12(1): 132. PMID: 35354798https://pubmed.ncbi.nlm.nih.gov/35354798/Brief Summary: This case control study identified widespread effects of fetal exposure to antenatal maternal glucocorticoid treatment on newborn bloodspot DNA methylation profiles.Antenatal treatment with glucocorticoids (AGC), such as betamethasone or dexamethasone, is widely u...

ey0017.12-7 | Type 2 Diabetes | ESPEYB17

12.7. Dissecting racial bias in an algorithm used to manage the health of populations

Z Obermeyer , B Powers , C, et al. Vogeli

To read the full abstract: Science 2019;366(6464):447-53. doi: 10.1126/science.aax2342Short summary: Dissecting racial bias in health care systems revealed that a type of software program, which determines who receives access to high-risk health care management, routinely accepts healthier whites ahead of blacks who are less healthy.Comment: The yea...

ey0017.13-14 | Endocrinology | ESPEYB17

13.14. Newborn screening in Nigeria: Will incorporating congenital hypothyroidism with sickle cell disease improve neonatal screening programme?

EY Iroro , J Tamunopriye , B Datonye , I Lorenzo

To read the full abstract: Acta Biomed. 2019; 90(2): 316–320. doi: 10.23750/abm.v90i2.8485• The authors review the present status of newborn screening in Africa and discuss the concept that adding a neonatal screening for congenital hypothyroidism (CH) to an existing sickle cell disease screening would make it easier to implement than developing an independent screening program.&...

ey0017.14-6 | (1) | ESPEYB17

14.6. How frequently are articles in predatory open access journals cited

B-C Bjork , S Kanto-Karvonen , JT Harviainen

To read the full abstract: Publications 2020;8:17Predatory journals, sometimes called write-only publishing or deceptive publishing, follow an exploitive academic publishing business model that involves charging publication fees to authors without checking articles for quality and legitimacy and without providing the other editorial and publishing services that legitimate academic journals provide, whether open access or not. Their numbers keep ...

ey0015.6-10 | Food for thought | ESPEYB15

6.10 I am your trans patient

EB Lewis , B Vincent , A Brett , S Gibson , RJ Walsh

To read the full abstract: BMJ. 2017 Jun 30;357:j2963This group of 5 transgender and non-medical professional authors has written a unique “What Your Patient is Thinking” article published in the BMJ. Their aim was to tell health care providers, and others who manage transgender people, how they want to be received and treated and what went wrong in many previous meetings with the healt...

ey0021.3-5 | Thyroid Function - Genetic Determinants and Associations with Health and (Thyroid) Disease | ESPEYB21

3.5. Multi-trait analysis characterizes the genetics of thyroid function and identifies causal associations with clinical implications

Sterenborg Rosalie B T M , Steinbrenner Inga , Li Yong

Brief Summary: This genome-wide association study (GWAS) meta-analysis of 271,040 European participants investigated the genetic determinants of thyroid function, including reference range serum TSH, FT4, free and total T3, proxies for metabolism (T3/FT4 ratio), as well as dichotomized high and low TSH levels. It identified 259 independent associations for TSH, 85 for FT4, and novel associations for thyroid hormone (TH) metabolism (T3/FT4 ratio). Genetic variants explained 14....