ESPE Yearbook of Paediatric Endocrinology

Sci Rep. 2022; 12(1): 7062. PMID: 35488035https://pubmed.ncbi.nlm.nih.gov/35488035/Brief Summary: This study provides evidence on the relationship between parental separation and hypertension at midlife and suggests interventions to enhance the psychological and cognitive development of girls who have experienced parental separation to help reduce multiple adverse health outcomes, including ...

To read the full abstract: BMJ. 2019;367:l6460. doi: 10.1136/bmj.l6460Short summary: There is wide variation around the world in how researchers manage their work-life balance.Comment: The Christmas edition of The BMJ published this observational study that examined more than 49 000 manuscripts and 76 000 peer review online submissions to The...

Brief summary: This study investigated the brain structure in young adult patients with autoimmune Addison’s disease (AAD). It found that patients with AAD had a 4.3% smaller total brain volume but no major differences in subcortical structures compared to healthy controls.Both short- and long-term disruptions in cortisol concentrations and rhythmicity affect brain structure development. Animal studies have shown that both pre- and postnatal disturb...

Brief Summary: This case-control study compared resting-state functional connectivity (rs-fc) of the brain between patients with autoimmune Addison’s disease (AAD) and healthy controls. The results suggest that AAD affects the baseline functional organization of the brain and that current treatment strategies of AAD may be a risk factor.Comment: Autoimmune Addison disease (AAD) is a form of primary adrenal insufficiency (PAI), in which autoimmune ad...

Nat Rev Endocrinol. 2020; 16(10): 578–589.https://pubmed.ncbi.nlm.nih.gov/32724183/In this review, the authors discuss the pathogenesis and treatment of primary aldosteronism (PA), the most frequent form of secondary hypertension (affecting 5% of patients with hypertension in primary care and 10–20% of those referred to specialist care). The pathophysiological basis of PA is auton...

Diabetologia. 2021 May;64(5):1121-1132. doi: 10.1007/s00125-020-05379-y. PMID: 33495846.Brief Summary: This longitudinal mother-infant dyad study assessed the risk of obesity at age 2-5 years in offspring who had been exposed to Gestational diabetes mellitus (GDM), were breastfed for either less or more than six months, and also exposed to sugar-sweetened beverages. ...

Front Endocrinol (Lausanne). 2022 Mar 24;13:832678. doi: 10.3389/fendo.2022.832678. PMID: 35399939.Brief Summary: This retrospective case note study assessed the impact of different classes of obesity on maternal and neonatal outcomes. Higher classes of maternal obesity were associated with increased rates of caesarean section, GDM and gestational hypertension and pre-eclampsia.<p class...

qhfka9357@naver.com Integr Med Res 11 (2022) 100832. doi: 10.1016/j.imr.2022.100832Brief Summary: This systematic review found that East Asian traditional medicine (EATM) therapies may have beneficial effects in children with idiopathic short stature, however, high-quality studies are necessary.The authors reviewed 14 studies (...

To read the full abstract: J Hepatol. 2019;71(4):802–10. doi: 10.1016/j.jhep.2019.06.023Short summary: Prediabetes is highly prevalent in Caucasian children and adolescents with well-characterized, biopsy-proven non-alcoholic fatty liver disease (NAFLD).Comment: NAFLD is considered the liver presentation of the metabolic syndrome. NAFLD enco...

J Pediatr Surg. 2019 Feb 22. pii: S0022-3468(19)30117–4.doi: 10.1016/j.jpedsurg.2019.01.062. PubMed PMID:30905417This literature review aimed to analyze the prevalence of gender dysphoria in 46,XX individuals with CAH raised female and male and to identify subgroups with a higher likelihood of gender dysphoria. In total 1770 papers published between 1988 ...