ESPE Yearbook of Paediatric Endocrinology

Brief Summary: This narrative review summarized 75 published studies on reproductive function in survivors of childhood, adolescent, and young adult Hodgkin lymphoma (HL). 41 papers reported on 5057 female HL survivors. Most young female survivors had regular menstrual cycles. The incidence of premature ovarian failure (POI) varied between 6-34%. Biochemical evidence for impaired ovarian reserve or function was frequent (low AMH 55–59%. elevated FSH 17–100%). 51 stud...

To read the full abstract: Crit Care Med. 2017; 45(12): 2078-2088This guideline replaces/updates the 2008 recommendations regarding the diagnosis and management of critical illness-related corticosteroid insufficiency (CIRCI) in adult and pediatric patients. In CIRCI, inadequate glucocorticoid-mediated anti-inflammatory activity is observed in relation to the severity of the critical illne...