ISSN 1662-4009 (online)

ey0021.7-2 | Clinical Guidance and Studies | ESPEYB21

7.2. Differentiation of idiopathic central precocious puberty from premature thelarche using principal component analysis

A Cleemann Wang , CP Hagen , TH Johannsen , AG Madsen , LH Cleemann , P Christiansen , KM Main , A Juul , RB Jensen

Brief Summary: this retrospective study describes clinical and biochemical parameters which, using the principal component analysis, help in the differential diagnosis between idiopathic central precocious puberty (ICPP) and premature thelarche (PT).Breast development in girls before 8 years of age may be related to progressive CPP but can sometimes simply be the consequence of premature thelarche without activation of the hypothalamic-pituitary-gonadal ...