ESPE Yearbook of Paediatric Endocrinology

To read the full abstract: The New England journal of medicine. 2019;380(22):2136–45.Here, Inge et al. explored whether the outcomes of Roux-en-Y gastric bypass (RYGB) differ according to the age of the patient at the time of surgery. They analysed retrospective data on the 5-year outcomes of RYGB in 161 adolescents from the Teen-LABS-study (1) and in 396 adults with a history...

To read the full abstract: N Engl J Med. 2019;380(22):2136–2145These authors describe the 5-year follow-up of a multicenter patient cohort of adolescents with severe obesity who underwent gastric bypass surgery to lose weight and improve cardiometabolic risk factors (the Teen-LABS study; n=161, age 13–19 years at time of surgery). They compared these data with a simila...

Brief summary: Emont et al. created a cell atlas of human and mouse white adipose tissue, which goes a long way in informing our understanding of the complexity of adipose tissue.Although adipocytes make up the largest proportion of adipose tissue volume, the cellular structure of adipose tissue is far more complex and includes adipose tissue progenitor cells (APCs), fibroblasts, vascular cells and immune cells. We are also beginning to understa...