ISSN 1662-4009 (online)

ey0021.13-14 | Identifying Health Disparities and Improving Access to Healthcare | ESPEYB21

13.14. Physical late effects of treatment among survivors of childhood cancer in low- and middle-income countries: a systematic review

KA Wong , A Moskalewicz , PC Nathan , S Gupta , A Denburg

Brief Summary: This systematic review investigated the physical residual effects of treatment on pediatric cancer survivors in low- and middle-income countries (LMICs), a topic with substantial information voids. Selection bias, limited sample sizes, and wide differences in the definition of long-term treatment effects were identified and these limited the ability to perform meta-analyses.In high-income countries (HICs), the 5-year survival rates followi...

ey0021.9-14 | Growth Problems in Cancer Survivors | ESPEYB21

9.14. Exploring height outcomes with adjuvant aromatase inhibition in growth hormone-deficient male survivors of childhood cancer

NI Pollock , M Song , AJ Wolf , Y Li , CP Hawkes , N Motamedi , MR Denburg , S Mostoufi-Moab

Brief Summary: This single-center, retrospective cohort study compared the final adult height (FAH) of 92 male childhood cancer survivors (CCS) with growth hormone deficiency GHD) treated with growth hormone alone (monotherapy) or in combination with an aromatase inhibitor. The addition of AI to GH therapy did not improve FAH.This study from the Children’s Hospital of Philadelphia is the most extensive study on the role of AI associated with GH in i...