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ey0021.12-13 | Lipid Metabolism | ESPEYB21

12.13. Influence of oral contraceptives on lipid profile and trajectories in healthy adolescents-data from the EVA-tyrol study

A Staudt , SJ Kiechl , N Gande , C Hochmayr , B Bernar , K Stock , R Geiger , A Egger , A Griesmacher , M Knoflach , U Kiechl-Kohlendorfer , Early Vascular Ageing (EVA) Study Group.

Brief Summary: In a large cohort of healthy adolescents, oral contraceptive (OC) users showed an higher LDL and triglyceride blood levels than non-users. Similarly, lipid trajectories over time showed an increase in LDL and triglyceride levels.Comment: Oral contraceptives (OCs) are widely used among young women. Studies in adults reported that OCs increase triglyceride levels, but effects on LDL levels were inconsistent. However, many of these studies we...

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ey0016.14-12 | (1) | ESPEYB16

14.12. Genome amplification and cellular senescence are hallmarks of human placenta development

P Velicky , G Meinhardt , K Plessl , S Vondra , T Weiss , P Haslinger , T Lendl , K Aumayr , M Mairhofer , X Zhu , B Schutz , RL Hannibal , R Lindau , B Weil , J Ernerudh , J Neesen , G Egger , M Mikula , C Rohrl , AE Urban , J Baker , M Knofler , J Pollheimer

To read the full abstract: PLoS Genet 2018;14:e1007698.These authors studied human placental and decidual tissues obtained from elective pregnancy terminations (612 weeks gestation). Placental extravillous trophoblasts (EVTs), the cells that rapidly invade the mothers endometrium, undergo an initial stage of genomewide amplification leadi...

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ESPE Yearbook of Paediatric Endocrinology

12.13. Influence of oral contraceptives on lipid profile and trajectories in healthy adolescents-data from the EVA-tyrol study

14.12. Genome amplification and cellular senescence are hallmarks of human placenta development

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