ISSN 1662-4009 (online)

ey0019.4-5 | Important for clinical practice | ESPEYB19

4.5. Oral nutritional supplementation improves growth in children at malnutrition risk and with picky eating behaviors

D Khanna , M Yalawar , PV Saibaba , S Bhatnagar , A Ghosh , P Jog , AV Khadilkar , B Kishore , AK Paruchuri , PD Pote , RD Mandyam , S Shinde , A Shah , DTT Huynh

Nutrients. 2021 Oct 14;13(10):3590. PMID: 34684591Brief Summary: This multi-center, prospective, randomized, double-blind study reports the effects of two different oral nutritional supplements (ONS) on growth in ‘picky eaters’ children at risk of malnutrition in India. Anthropometric measures (weight, height, weight-for-height, body mass index (BMI), and mid-upper-arm circumference were evaluated at day 1, 30, 60 and 90. Both types of...

ey0021.8-13 | New Hope | ESPEYB21

8.13. The role of interferon-[gamma] in autoimmune polyendocrine syndrome Type 1

V Oikonomou , G Smith , GM Constantine , MM Schmitt , EMN Ferre , JC Alejo , D Riley , D Kumar , Dias L Dos Santos , J Pechacek , Y Hadjiyannis , T Webb , BA Seifert , R Ghosh , M Walkiewicz , D Martin , M Besnard , BD Snarr , S Deljookorani , CR Lee , T DiMaggio , P Barber , LB Rosen , A Cheng , A Rastegar , AA de Jesus , J Stoddard , HS Kuehn , TJ Break , HH Kong , L Castelo-Soccio , B Colton , BM Warner , DE Kleiner , MM Quezado , JL Davis , KP Fennelly , KN Olivier , SD Rosenzweig , AF Suffredini , MS Anderson , M Swidergall , C Guillonneau , LD Notarangelo , R Goldbach-Mansky , O Neth , MT Monserrat-Garcia , J Valverde-Fernandez , JM Lucena , AL Gomez-Gila , A Garcia Rojas , MRJ Seppanen , J Lohi , M Hero , S Laakso , P Klemetti , V Lundberg , O Ekwall , P Olbrich , KK Winer , B Afzali , NM Moutsopoulos , SM Holland , T Heller , S Pittaluga , MS Lionakis

Brief Summary: This study suggests that excessive interferon-γ–mediated responses have a pathogenic role in APS-1 and provides the foundation for therapies that affect interferon-γ–mediated disease.Commentary: Autoimmune polyendocrine syndrome type 1 (APS-1), also known as autoimmune polyendocrinopathy, candidiasis, and ectodermal dystrophy (APECED), is an autosomal recessive multiorgan syndrome caused by loss-of-function variants in ...