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ey0019.3-4 | Thyroid development | ESPEYB19

3.4. Transcriptomic signature of human embryonic thyroid reveals transition from differentiation to functional maturation

G Dom , P Dmitriev , MA Lambot , Vliet G Van , D Glinoer , F Libert , A Lefort , JE Dumont , C Maenhaut

Front Cell Dev Biol. 2021 Jun 11;9:669354. doi: 10.3389/fcell.2021.669354. eCollection 2021. PMID: 34249923Brief Summary: This in vitro study analyzed the transcriptome of the developing thyroid gland in human embryonic thyroids compared to non-thyroidal human embryonic tissues and adult thyroid and adult non-thyroidal tissues. They identified four differently regulated sets of gen...

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ey0018.3-4 | Thyroid development | ESPEYB18

3.4. Single-cell transcriptome analysis reveals thyrocyte diversity in the zebrafish thyroid gland

P Gillotay , M Shankar , B Haerlingen , E Sema Elif , M Pozo-Morales , I Garteizgogeascoa , S Reinhardt , A Krankel , J Blasche , A Petzold , N Ninov , G Kesavan , C Lange , M Brand , A Lefort , F Libert , V Detours , S Costagliola , S Sumeet Pal

EMBO Rep. 2020;21:e50612. doi: 10.15252/embr.202050612.This zebrafish study identified and molecularly characterized adult transcriptionally different thyrocyte subpopulations even within the same follicle.It is well established that within a thyroid gland, follicles are heterogenous concerning functional activity. More active follicles are characterized by a high co...

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ESPE Yearbook of Paediatric Endocrinology

3.4. Transcriptomic signature of human embryonic thyroid reveals transition from differentiation to functional maturation

3.4. Single-cell transcriptome analysis reveals thyrocyte diversity in the zebrafish thyroid gland

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