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ey0015.13-3 | How does paediatric endocrinology and diabetes fit in the global initiatives? | ESPEYB15

13.3 Effects of the Informed Health Choices primary school intervention on the ability of children in Uganda to assess the reliability of claims about treatment effects: a cluster-randomised controlled trial

A Nsagni , D Semakula , AD Oxman , A Austvoll-Dahlgren , M Oxman , S Rosenbaum , A Morelli , C Glenton , S Lewin , M Kaseje , I Chalmers , A Fretheim , Y Ding , NK Sewankambo

To read the full abstract: Lancet 2017; 390: 374-88See comment on 13.4...

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ey0015.13-4 | How does paediatric endocrinology and diabetes fit in the global initiatives? | ESPEYB15

13.4 Effects of the Informed Health Choices podcast on the ability of parents of primary school children in Uganda to assess claims about treatment effects: a randomised controlled trial

D Semakula , A Nsangi , AD Oxman , M Oxman , A Austvoll-Dahlgren , S Rosenbaum , A Morelli , C Glenton , S Lewin , M Kaseje , I Chalmers , A Fretheim , DT Kristoffersen , NK Sewenkambo

To read the full abstract: Lancet 2017; 390(10092): 389-398[Comment on 13.3 & 13.4] Access to quality medical care is often difficult in resource-limited settings and depends upon the collaboration of key stakeholder groups, including global/regional health policymakers, national governments and health system managers, the pharmaceutical industry and trained clinicians and health work...

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ey0020.5-12 | Basic Research | ESPEYB20

5.12. Defective jagged-1 signaling affects GnRH development and contributes to congenital hypogonadotropic hypogonadism

L Cotellessa , F Marelli , P Duminuco , M Adamo , GE Papadakis , L Bartoloni , N Sato , M Lang-Muritano , A Troendle , WS Dhillo , A Morelli , G Guarnieri , N Pitteloud , L Persani , M Bonomi , P Giacobini , V Vezzoli

Brief summary: Using a combination of expression studies in human embryos as well as functional studies in zebrafish and genetic sequencing of patient with congenital hypogonadotropic hypogonadism, this study identified a novel role for Jag1/Notch signaling in the development of GnRH neurons.GnRH neurons have a unique characteristic as they start life in the olfactory placode and then migrate into the hypothalamus during embryonic development, thanks to ...

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ESPE Yearbook of Paediatric Endocrinology

13.3 Effects of the Informed Health Choices primary school intervention on the ability of children in Uganda to assess the reliability of claims about treatment effects: a cluster-randomised controlled trial

13.4 Effects of the Informed Health Choices podcast on the ability of parents of primary school children in Uganda to assess claims about treatment effects: a randomised controlled trial

5.12. Defective jagged-1 signaling affects GnRH development and contributes to congenital hypogonadotropic hypogonadism

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