ESPE Yearbook of Paediatric Endocrinology

Int J Obes (Lond). 2020 Oct;44(10):2011–2022. 10.1038/s41366-020-0644-1. https://pubmed.ncbi.nlm.nih.gov/32713944/Schur et al. addressed the question, whether responsiveness to visual food cues in functional magnetic resonance imaging (fMRI) is related to the treatment success of a 6-month Family-based Behavioral Treatment (...

To read the full abstract: Nat Rev Endocrinol 2018;14:301-316The authors provide complete information as far as available on the prevalence of hypothyroidism, hyperthyroidism and iodine deficiency all over the world. Nutritional iodine is a key determinant of thyroid disease risk. Further factors influencing thyroid disease prevalence are smoking, ageing, genetic susceptibility, and endo...

Brief Summary:This study in mice and humans shows how paternal overweight at conception affects the metabolism of their offspring. Sperm-borne mt-sncRNAs (mitochondrial encoded or derived small non-coding RNAs) are altered by a 2-week high fat diet (HFD) challenge in mice, likely through specific upregulation of mt-tsRNAs (mitochondrial transfer RNAs) caused by mitochondrial dysfunction. In humans, mt-tsRNAs in spermatozoa correlate with body mass index. Genetically engineered...