ESPE Yearbook of Paediatric Endocrinology

ESPE Yearbook of Paediatric Endocrinology

ISSN 1662-4009 (online)

Published by BioScientifica

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ey0016.11-6 | Tracking, Programming, and Epigenetics | ESPEYB16

11.6. Adipose tissue mitochondrial dysfunction in human obesity is linked to a specific DNA methylation signature in adipose-derived stem cells

M Ejarque , V Ceperuelo-Mallafre , C Serena , E Maymo-Masip , X Duran , A Diaz-Ramos , M Millan-Scheiding , Y Nunez-Alvarez , C Nunez-Roa , P Gama , PM Garcia-Roves , MA Peinado , JM Gimble , A Zorzano , J Vendrell , S Fernandez-Veledo

To read the full abstract: Int J Obes (Lond). 2019;43(6):1256–1268This epigenome-wide association study in stromal/stem cells (ASCs), derived from subcutaneous adipose tissue samples of lean and obese subjects, revealed a specific DNA methylation signature in adipocyte precursors associated with obesity, which has a significant impact on the metabolic phenotype and the mitochondrial...
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Published by BioScientifica

ESPE Yearbook of Paediatric Endocrinology
ISSN 1662-4009 (Online)
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