ESPE Yearbook of Paediatric Endocrinology

Brief Summary: This review combined findings from human and rodent studies on the maternal factors that influence the neurodevelopmental programming of long-term adiposity. It highlights the roles of maternal nutritional status, metabolic hormones and epigenetic changes during gestation and the postnatal period on the programming of body weight in the offspring, and their impact on the development of hypothalamic, brain stem, and hedonic circuits within the central nervous sys...