ESPE Yearbook of Paediatric Endocrinology

ESPE Yearbook of Paediatric Endocrinology

ISSN 1662-4009 (online)

Published by BioScientifica

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ey0017.4-13 | New paradigms | ESPEYB17

4.13. IGF1-mediated human embryonic stem cell self-renewal recapitulates the embryonic niche

SE Wamaitha , KJ Grybel , G Alanis-Lobato , C Gerri , S Ogushi , A AMcCarthy , SK Mahadevaiah , L Healy , RA Lea , M Molina-Arcas , LG Devito , K Elder , P Snell , L Christie , J Downward , JMA Turner , KK Niakan

To read the full abstract: Nat Commun. 2020 Feb 7;11(1):764.The signaling pathways involved in the regulation of early human development are largely unknown and the IGF system has been proposed to play a major role (1). The knowledge of mechanisms and actors involved in early life development is crucial to develop successful strategies for maintaining pluripotent human embryonic stem cells (hESCs).This sophisticated study ...
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Published by BioScientifica

ESPE Yearbook of Paediatric Endocrinology
ISSN 1662-4009 (Online)
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