ISSN 1662-4009 (online)

ey0017.14-14 | (1) | ESPEYB17

14.14. T cell-mediated regulation of the microbiota protects against obesity

C Petersen , R Bell , KA Klag , S-H Lee , R Soto , A Ghazaryan , K Buhrke , HA Ekiz , KS Ost , S Boudina

To read the full abstract: Science 2019;365:eaat9351.As in humans, weight gain in mice leads to fatty liver disease, inflammatory adipose tissue, and insulin resistance. The depletion of the microbiota through antibiotic treatment rescued this weight gain. The cohousing of T-Myd88–/– mice transferred the weight gain to wild-type mice. The major feature of the microbiota formed within T-Myd88–/– mice was a reduction in Clostri...

ey0019.9-16 | Bone health in chronic disease | ESPEYB19

9.16. Skeletal adverse events in childhood cancer survivors: An adult life after childhood cancer in Scandinavia cohort study

T Oskarsson , AK Duun-Henriksen , A Bautz , S Montgomery , A Harila-Saari , C Petersen , R Niinimaki , L Madanat-Harjuoja , L Tryggvadottir , AS Holmqvist , H Hasle , M Heyman , JF Winther , ALiCCS study group

trausti.oskarsson@ki.se Int J Cancer. 2021; 149: 1863-1876. PMID: 34278568.Brief Summary: This population-based study retrospectively compared hospital admissions for skeletal issues in a group of 26,334 cancer survivors (CCS) diagnosed before 20 years of age and 127,531 matched controls. 1,987 CCS vs 8,986 controls had at least one skeletal adverse event. Total hospitalization rate ratio (RR) for ske...