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ey0021.9-2 | Fertility Issues | ESPEYB21

9.2. Effects of radiation therapy on the female reproductive tract in childhood cancer survivors: a PENTEC comprehensive review

C Hill-Kayser , E Yorke , A Jackson , C Gracia , J Ginsberg , K Keene , C Ronckers , ML Metzger , Z Li , LS Constine , CH Hua

Brief Summary: This paper reviewed the toxicity of radiation therapy (RT) on ovarian, uterine and vaginal tissue in childhood cancer survivors (CCSs), using data published from 1970 to 2017. Overall, 11 studies reported data on ovarian damage, 8 on uterine volume related to treatment, and 3 on vaginal effects. Most studies did not report accurate dosimetric data and dose-volume relationships, and the confounder role of chemotherapy was not considered. In general, published dat...

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ey0018.9-6 | Surveillance strategies of endocrine complications | ESPEYB18

9.6. Female reproductive function after treatment of childhood acute lymphoblastic leukemia

R Roshandel , M van Dijk , A Overbeek , G Kaspers , C Lambalk , C Beerendonk , D Bresters , M van der Heiden-van der Loo , M van den Heuvel-Eibrink , L Kremer , J Loonen , H van der Pal , C Ronckers , W Tissing , B Versluys , F van Leeuwen , M van den Berg , E van Dulmen-den Broeder

Pediatr Blood Cancer. 2021; 68: e28894. https://pubmed.ncbi.nlm.nih.gov/33459500/This cross-sectional observational study examined reproductive function in a nationwide cohort of female childhood acute lymphoblastic leukemia (ALL) survivors.Self-reported reproductive characteristics (age at menarche, virginity status, desire for children, pregnancy rates, and adverse ...

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ESPE Yearbook of Paediatric Endocrinology

9.2. Effects of radiation therapy on the female reproductive tract in childhood cancer survivors: a PENTEC comprehensive review

9.6. Female reproductive function after treatment of childhood acute lymphoblastic leukemia

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