ISSN 1662-4009 (online)

ey0021.12-5 | Improving T2D Outcomes | ESPEYB21

12.5. The efficacy and safety of GLP-1 receptor agonists in youth with type 2 diabetes: a meta-analysis

LBT Yugar , LG Sedenho-Prado , Ferreira IMC da Silva , CAM Silva , AC Sposito , C Cercato

Brief Summary: This meta-analysis including 415 children and adolescents with T2D showed that GLP-1 receptor agonists reduced HbA1c by 1%, fasting blood glucose, and body weight by 1.6 kg, with no notable impact on blood pressure. An increased incidence of mainly gastrointestinal side effects was observed.Comment: Over the past decade, glucagon-like peptide 1 (GLP-1) receptor agonists have revolutionized the management of T2DM in adults.1 Thes...