ESPE Yearbook of Paediatric Endocrinology

Brief summary: This Danish single-center retrospective study evaluated the occurrence of pathological findings on neuroimaging among children diagnosed with central precocious puberty (CPP).CPP incidence has been increasing over the last four decades (1) and is more prevalent in females than in males. Most cases are idiopathic (2) but brain magnetic resonance imaging (MRI) is routinely performed in order to exclude rare pathological causes.<p class="...

Brief Summary: This retrospective study of 123 Danish girls treated with GnRHa for idiopathic central precocious puberty (CPP) shows that GnRH agonists do not impact body mass index during and after cessation of treatment.The use of GnRH agonists (GnRHa) for treatment of girls with CPP is well established but the potential long term effects of GnRHa remain a matter of debate, especially regarding their impact on weight evolution1,2.<p clas...