ey0015.2-19 | Novel mechanisms of islet dysfunction in intrauterine growth restricted rats | ESPEYB15
CS Rashid
, YC Lien
, A Bansal
, LJ Jaeckle-Santos
, C Li
, KJ Won
, RA Simmons
To read the full abstract: Endocrinology. 2018 Feb 1;159(2):1035-1049Placental insufficiency leads to intrauterine growth restriction (IUGR) which in the fetus leads to hypoxemia and hypoglycemia. IUGR fetuses are charaterised by having higher circulating catecholamine concentrations and lower circulating insulin concentrations, as well as impaired glucose stimulated insulin secretion. In cases o...