ey0021.5-14 | Advances in Growth, Bone Biology and Mineral Metabolism | ESPEYB21
Lamande Shireen R.
, Ng Elizabeth S.
, Cameron Trevor L
, Kung Louise H. W.
, Sampurno Lisa
, Rowley Lynn
, Lilianty Jinia
, et al.
In brief. This basic research study used an in vitro method to recapitulate key steps in growth plate development and endochondral bone formation, using induced pluripotent stem cells (iPSCs). This method provides original material that can be used to study growth plate and bone development, to assess the consequences of genetic variants involved in bone diseases, and to test new therapies.Commentary: In vertebrates, the longitudinal growth of l...