ISSN 1662-4009 (online)

ey0021.12-4 | Improving T2D Outcomes | ESPEYB21

12.4. Continuous glucose monitoring versus standard of care in adolescents with type 2 diabetes: a pilot randomized cross-over trial

N Chang , ROB Barber , J Llovido Alula , R Durazo-Arvizu , LC Chao

Brief Summary: This pilot study assessed the feasibility and impact of continuous glucose monitoring (CGM) in 9 adolescents with T2D. CGM use lowered HbA1c by up to 3.8% in participants who consistently used the device.Comment: Large cohort studies investigating complications in children and adolescents with T2D have clearly shown a higher incidence of complications compared to both adults with T2D and children with type 1 diabetes (T1D). These complicat...

ey0015.2-13 | Primary cells isolated from the umbilical cord of offspring born to mothers with GDM maintain metabolic and molecular imprints of maternal hyperglycemia | ESPEYB15

Primary cells isolated from the umbilical cord of offspring born to mothers with GDM maintain metabolic and molecular imprints of maternal hyperglycemia

AI Amrithraj , A Kodali , L Nguyen , AKK Teo , CW Chang , N Karnani , KL Ng , PD Gluckman , YS Chong , W Stünkel

To read the full abstract: Endocrinology. 2017 Jul 1;158(7):2102-2112Gestational diabetes mellitus (GDM) produces fetal hyperglycemia with increased lifelong risks for the exposed offspring to cardiovascular and other diseases. In-utero exposure to GDM alters metabolic programming in newborns and their placenta, cord tissues, and cord blood. Human umbilical cord mesenchymal stromal cells (hUC-MSCs...