ESPE Yearbook of Paediatric Endocrinology

ESPE Yearbook of Paediatric Endocrinology

ISSN 1662-4009 (online)

Published by BioScientifica

Page 1 of about 2 results

ey0015.2-3 | Mutations in the FOXA2 gene link beta cell dysfunction with Hypopituitarism | ESPEYB15

Mutations in the FOXA2 gene link beta cell dysfunction with Hypopituitarism

ME Vajravelu , J Chai , B Krock , S Baker , D Langdon , C Alter , DD De León

To read the full abstract: J Clin Endocrinol Metab. 2018 Mar 1;103(3):1042-1047See Comment under 2.4....
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ey0019.15-15 | Basic Science and Genetics | ESPEYB19

15.15. Accurate prediction of protein structures and interactions using a three-track neural network

M Baek , F DiMaio , I Anishchenko , J Dauparas , S Ovchinnikov , GR Lee , J Wang , Q Cong , LN Kinch , RD Schaeffer , C Millan , H Park , C Adams , CR Glassman , A DeGiovanni , JH Pereira , AV Rodrigues , Dijk AA van , AC Ebrecht , DJ Opperman , T Sagmeister , C Buhlheller , T Pavkov-Keller , MK Rathinaswamy , U Dalwadi , CK Yip , JE Burke , KC Garcia , NV Grishin , PD Adams , RJ Read , D Baker

Science. 2021;373(6557):871-6. doi: 10.1126/science.abj8754 PubMed ID: 34282049Brief summary: This study reveals a Deep Learning method, ‘RoseTTA fold’, based on DeepMind’s Alphafold2 framework, to predict 3-dimensional protein structures from 1-dimensional sequence information and generate models of protein–protein complexes with high accuracy.Previ...
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ESPE Yearbook of Paediatric Endocrinology
ISSN 1662-4009 (Online)
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