ESPE Yearbook of Paediatric Endocrinology

ESPE Yearbook of Paediatric Endocrinology

ISSN 1662-4009 (online)

Published by BioScientifica

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ey0016.12-14 | Lipid Metabolism | ESPEYB16

12.14. An integrative systems genetic analysis of mammalian lipid metabolism

BL Parker , AC Calkin , MM Seldin , MF Keating , EJ Tarling , P Yang , SC Moody , Y Liu , EJ Zerenturk , EJ Needham , ML Miller , BL Clifford , P Morand , MJ Watt , RCR Meex , KY Peng , R Lee , K Jayawardana , C Pan , NA Mellett , JM Weir , R Lazarus , AJ Lusis , PJ Meikle , DE James , TQ de Aguiar Vallim , BG Drew

Nature 2019;567:187–193.URL https://doi.org/10.1038/s41586-019-0984-ySummary: Novel diagnostic and prognostic biomarkers in the blood that can predict early fatty liver disease were identified, using a proteomic and lipidomic-wide systems genetic approach in 107 genetically distinct mouse strains. In addition, the novel lipid-regulatory protein, PSMD9, was identified as...
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ESPE Yearbook of Paediatric Endocrinology
ISSN 1662-4009 (Online)
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